Validation of Heel Stick Microsampling To Optimize Micafungin Doses in Neonates and Young Infants
نویسندگان
چکیده
منابع مشابه
Population pharmacokinetics of micafungin in neonates and young infants.
Micafungin is an echinocandin with potent activity against Candida spp. Hematogenous Candida meningoencephalitis (HCME) is a frequent complication of disseminated Candida infection in premature infants. A preclinical model of HCME suggests that micafungin may be an effective agent for this syndrome, but relatively high weight-based dosages are required. This prompted the further study of the sa...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2018
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01199-18